Gabapentinoid consumption in 65 countries and regions from 2008 to 2018: a longitudinal trend study.

Nat Commun · 2023 · PMC10435503 · PMID 37591833

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an increasing trendno p-value reported

In a recent study conducted in the US, around 95% of gabapentin prescriptions in the US were for off-label pain management use and an increasing trend of overlapping use with opioid analgesics has also been observed 11 , despite strong evidence suggesting an increase in the risk of all-cause and drug-related hospitalisations from this combination 11 , 12 .

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