It contains two collagen genes (COL11A2, COL2A1) several solute carrier genes (SLC8A3, SLC13A5, SLC36A2) which have been shown to be prognostic in osteosarcoma 54 , and genes involved in Wnt signaling (APCDD1L, BARX1) which might be significant given the oncogenic role Wnt signaling plays in osteosarcoma 55 , 56 .
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Transcriptional profiling of canine osteosarcoma identifies prognostic gene expression signatures with translational value for humans.
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