SNPs in cytochrome P450 genes decide on the fate of individuals with genetic predisposition to Parkinson's disease.

Front Pharmacol · 2023 · PMC10436510 · PMID 37601072

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highly significantno p-value reported

When analyzing the data from the PPMI database, we were first of all surprised that GPD as well as GUN individuals showed much more highly significant SNPs (OR > 5 and OR < 0.2) in their P450 genes than IPD patients when compared with healthy individuals ( Hartz et al., 2022 ).

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