Computational modeling allows unsupervised classification of epileptic brain states across species.

Testing the mean sensitivity and PPV across datasets of each species for significance, we find that classification results are always highly significant ( p < 0.01, for group level permutation testing against classification performance for Markov chain simulations, see Methods: Statistical Analysis), with mean ± STD sensitivity in the model: 0.99, rat: 0.73 ± 0.07, or human: 0.45 ± 0.15, and PPV in the model: 0.99, rat: 0.79 ± 0.16, or human: 0.56 ± 0.10.

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