Recombinant-attenuated Salmonella enterica serovar Choleraesuis vector expressing the PlpE protein of Pasteurella multocida protects mice from lethal challenge.

BMC Vet Res · 2023 · PMC10439597 · PMID 37598169

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highly significantno p-value reported

A highly significant Th-1 response was observed, evident by the higher IFN-γ levels induced, in the rSC0016(pS-PlpE) group compared to the inactivated vaccine group’s response, while the inactivated vaccine group responded with a significant Th-2 response, shown by the higher IL-4 concentration, compared to the rSC0016(pS-PlpE) group, which would be expected for a parenterally administered antigen.

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