Cycles of goal silencing and reactivation underlie complex problem-solving in primate frontal and parietal cortex.

Although the interaction was not significant, post hoc simple effect analyses confirmed that the aforementioned trend was highly significant in prefrontal cells (simple effect of cycle, F 3, 2244 = 11.3, P < 10 −4 ), with inferior parietal cells showing a similar but more moderate trend ( F 3, 2244 = 3.32, P = 0.02).

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