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Causes of Drug-Induced Severe Cutaneous Adverse Reaction Epidermal Necrolysis (EN): An Analysis Using FDA Adverse Event Reporting System (FAERS) Database.

Clin Cosmet Investig Dermatol · 2023 · PMC10440110 · PMID 37605788

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an increasing trendno p-value reported
The analysis of other antibiotics, monoclonal antibodies, and proton pump inhibitors, as well as others, such as antigout drugs, immunosuppressants, diuretic drugs, selective calcium channel blockers, chemotherapy for cancer, and antimalarial drugs (as detailed in Tables 1–3 and Figures 1–2 ) demonstrated an increasing trend over time.

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