Notably, we measured the levels of pro-inflammatory mediators in the spinal cord of rats 7 days after injury, and the results showed a decreasing trend of TNF-α, IL-1β, and IL-6 in the P-Exos-138 group compared to that in the SCI group ( Figures 5F–H ).
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Thermos-responsive hydrogel system encapsulated engineered exosomes attenuate inflammation and oxidative damage in acute spinal cord injury.
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