western blot analysis results indicated that CoCl 2- administration induced a highly significant elevation in HIF1-α, TGF-β, Smad-2, AKT and Bax protein expressions with a concomitant significant decrease in Bcl2 expression in hepatic tissue compared with the control value.
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Impact of HIF1-α/TGF-β/Smad-2/Bax/Bcl2 pathways on cobalt chloride-induced cardiac and hepatorenal dysfunction.
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