In mice treated with CD47 blockade, the glomerular infiltrating Ly6B + neutrophils showed an increasing trend ( Figure 5C ), implying that activated macrophages exhibiting efferocytosis may promote the recruitment of immune cells beyond those needed for focal cellular waste disposal.
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CD47 blockade ameliorates autoimmune vasculitis via efferocytosis of neutrophil extracellular traps.
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