Current status and temporal trend in incidence, death, and burden of esophageal cancer from 1990-2019.

Thorac Cancer · 2023 · PMC10447176 · PMID 37443420

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an increasing trendno p-value reported

Central Asia has experienced the greatest decrease in the ASIR and ASDR of EC, the countries of Central Europe had a steady ASIR and High‐Income North America had an increasing trend in ASIR and ASDR.

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a decreasing trendno p-value reported

The burden of EC shows a decreasing trend worldwide.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.