Interplay of Transforming Growth Factor-Beta 1 and 3 in the Pathogenesis of Oral Submucous Fibrosis and Its Malignant Transformation: An Immunohistochemical Study.

Cureus · 2023 · PMC10448117 · PMID 37637625

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highly significantp < 0.001actually significant

TGF-β1 versus TGF-β3 expression in NOM, OSF (stage 1 to stage 4), and OSCC with and without OSF TGF-β3 expression showed a highly significant increase in both epithelial and connective tissue compared to TGF-β1 in all groups (p < 0.001) (Table 3 , Figure 3 ).

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