Exonic mutations in cell-cell adhesion may contribute to CADASIL-related CSVD pathology.

Hum Genet · 2023 · PMC10449969 · PMID 37422595

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highly significantno p-value reported

TRAPD burden test Based on these results, cell–cell adhesion was chosen as it was the top hit for the GO-PANTHER slim biological processes (FDR 1.52 × 10 –5 ) and confirmation analysis using the different TOPPGene algorithm also found it highly significant (FDR 4.84 × 10 –5 ).

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