Micro- and Macrovascular Effects of Inflammation in Peripheral Artery Disease-Pathophysiology and Translational Therapeutic Approaches.

In a large, randomised placebo-controlled trial in patients with established CVD or several risk factors for the development of CVD and elevated triglyceride levels, the addition of IPE to standard statin treatment resulted in a highly significant risk reduction (HR 0.75) for ischaemic events and cardiovascular death when compared to placebo [ 283 ].

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