Targeting Conserved Pathways in 3D Spheroid Formation of Diverse Cell Types for Translational Application: Enhanced Functional and Antioxidant Capacity.

Cells · 2023 · PMC10453086 · PMID 37626861

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2D via gene set enrichment analysis (GSEA) revealed highly significant enrichment and downregulation of cell cycle pathways, E2F target (G1 phase) and G2/M checkpoint, in all three cell types after 3D culture conditions ( Figure 1 E).

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