Barely Significant
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Comparative analysis of multiorgan toxicity induced by long term use of disease modifying anti-rheumatic drugs.

PLoS One · 2023 · PMC10456141 · PMID 37624868

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highly significantno p-value reported
Higher serum creatinine reduced the GFR, and highly significant reduction was noticed by MTX. on the contrary, MTX lowered the level of urinary uric acid and urinary urea, resulting in the less inflammation and disease severity.

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