Integrated Analysis of Metabolomics Combined with Network Pharmacology and Molecular Docking Reveals the Effects of Processing on Metabolites of <i>Dendrobium officinale</i>.

The contents of polysaccharide in F, S and P were 398.60 mg/g, 354.20 mg/g and 316.47 mg/g, respectively, as illustrated in Figure 2 a, indicating a decreasing trend with a significant difference ( p < 0.01).

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The results of changes in the relative abundance of metabolites showed that there were seven metabolites, including eriodictyol, hesperetin, naringenin, bilirubin, diosmetin, citreorosein and mulberrofuran Q, which have potential anticoagulant, hypoglycemic and tumor inhibition activities, with an increasing trend in the “Fengdou” product.

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