Association of Soluble Markers of Inflammation With Peri-coronary Artery Inflammation in People With and Without HIV Infection and Without Cardiovascular Disease.

Both of these models were considered among tertiles of plasma marker concentrations and in both unadjusted and adjusted analyses, and those significant and borderline significant associations between soluble inflammatory markers (CD14, CD163, hs-CRP, TNFR-I, TNFR-II, IP-10, CCL2, CCL5, and CX3CL1) and peri-coronary inflammation suggest targets for further investigation in mechanistic studies.

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Of the plasma levels of inflammatory markers examined, levels of CCL2 ( P = .046) and soluble CD163 ( P = .008) were significantly higher in PWH than in PWoH, with a nonsignificant trend toward more IP-10 among PWH ( Supplementary Table 1 ).

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