Tryptophan metabolite norharman secreted by cultivated Lactobacillus attenuates acute pancreatitis as an antagonist of histone deacetylases.

BMC Med · 2023 · PMC10463520 · PMID 37635214

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a decreasing trendno p-value reported

As a result, the docking scores (Kcal/mol) of HDAC1-4 showed a decreasing trend; thus, HDAC4 possessed the best binding ability with the norharman compounds.

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