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Extracellular matrix turnover biomarkers reflect pharmacodynamic effects and treatment response of adalimumab in patients with axial spondyloarthritis-results from two randomized controlled trials.

Arthritis Res Ther · 2023 · PMC10463764 · PMID 37626399

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a numerical trendno p-value reported
After 12 weeks of treatment in the DANISH study, the biomarker levels showed a numerical trend to be lower or equal in BASDAI50 responders vs non-responders, in patients with ASDAS ≥ CII, ASDAS CII, or ASDAS MI vs ASDAS NI, respectively.

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