Since the incidence of IES-positive cases in perihilar eCCAs was low, most of the IES-positive cases in previous studies were invasive IPNBs, and IES-negative cases were conventional perihilar eCCAs; therefore, the differences in patient outcomes might be significant.
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Novel insights into the intraepithelial spread of extrahepatic cholangiocarcinoma: clinicopathological study of 382 cases on extrahepatic cholangiocarcinoma.
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