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BACE2: A Promising Neuroprotective Candidate for Alzheimer's Disease.

J Alzheimers Dis · 2023 · PMC10473127 · PMID 36463454

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a worrying trendno p-value reported
This is a worrying trend of global concern as dementia remains incurable and is permanently incapacitating that consequently exacts high disease and socio-economic burden throughout the patient’s remaining lifetime.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.