Assessing seizure liability <i>in vitro</i> with voltage-sensitive dye imaging in mouse hippocampal slices.

Front Cell Neurosci · 2023 · PMC10481167 · PMID 37680865

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an increasing trendno p-value reported

Although an increasing trend was observed at a high concentration (100 μM) of 4AP ( Figure 2Cii ), the cumulative increase of 4-AP dose concentration from low to high might explain this discrepancy.

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a decreasing trendno p-value reported

On the other hand, Pilo demonstrated a decreasing trend in the average PR-ratio at middle and low or higher concentrations (30 and ≥10 μM) for weak and saturation stimuli, respectively.

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