In contrast to our previous findings, increased efficiency in gene silencing that produces approximately 80% ABCF1 knockdown led to a decreasing trend in Poly(I:C) induced secretion of IL-8 when compared to silencing control.
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TNF-α and Poly(I:C) induction of A20 and activation of NF-κB signaling are independent of ABCF1 in human airway epithelial cells.
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