A Network Landscape of HPVOPC Reveals Methylation Alterations as Significant Drivers of Gene Expression via an Immune-Mediated GPCR Signal.

This analysis demonstrated that there was highly significant overlap between the genes for DEG-splicing and DEG-methylation (−log( p ) = 13; p = 2 × 10 −6 for both) and between CNV and SNV genes (−log( p ) = 3.1; p = 0.045) (significant = score > 3 = −log (0.05) for p = 0.05) ( Figure 1 A).

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