highly significantp -value < 0.0001
Among 48 cytokines/chemokines, evaluated by multiplex analysis in patient plasma, 6 (IL-6, CXCL-10, HGF, MIG, MCP-1, and G-CSF; Supplementary Table S2 ) were identified as highly significant in COVID-19 patients compared to non-COVID-19 respiratory disease controls ( p -value < 0.0001) ( Figure 2 ).