This resulted in highly significant inhibition of tumour growth (mean size ± SEM 4.90 ± 1.11 mm 2 ) compared to mice receiving untransduced T cells (67.23 ± 6.30 mm 2 ) at d27 post-tumour injection (Fig. 7a ).
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Pre-clinical validation of a pan-cancer CAR-T cell immunotherapy targeting nfP2X7.
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