While subject scores for the primary pattern (DurIV_PC1) did not differ for DurIV patients compared to healthy control subjects (p = 0.19; Student’s t -test and p = 0.43; Dunnett’s test), these values reached significance or marginal significance corrected for multiple comparison when computed in PD patients in the immediately earlier (DurIII) and later (DurV) PD groups compared to corresponding healthy control scores (p = 0.04 and p = 0.01, respectively, for Student’s t -tests, and p = 0.05 and p = 0.04, respectively, for the post-hoc Dunnett’s test) ( Fig.
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Parkinson's disease progression: Increasing expression of an invariant common core subnetwork.
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