Meanwhile, we detected the expression level of Bcl2, Bax, and cleaved caspase 3, and observed that the expression level of Bax and cleaved caspase 3 in the mutant group decreased compared to the wild-type group, while the expression level of Bcl2 showed an increasing trend in the mutant group ( Fig. 4 J, K).
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SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer.
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