A decreasing trend in the number of scale buds was also observed in the case of a 72-h exposure to RA (batch C72, Fig. 2I ) although results are not statistically significant (see Table 1 and Table S2 ), probably due to the dispersion of values and the low number of embryos.
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Interference with the retinoic acid signalling pathway inhibits the initiation of teeth and caudal primary scales in the small-spotted catshark <i>Scyliorhinus canicula</i>.
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