Changes in the skin microbiome during male maturation from 0 to 25 years of age.

As healthy males transition from infancy to adolescence, there is a decreasing trend in the abundance of Streptococcus ( p ‐value < 0.001) and Rothia ( p ‐value < 0.001) on the cheek skin.

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Actinobacteria showed an increasing trend during the maturing process, and Proteobacteria showed a comparable percentage of abundance in the first three groups, with a significant decrease in the 20–25 years group ( p ‐value < 0.01).

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