INTRODUCTION Recurrent miscarriage (RM) is generally defined as three or more consecutive clinical pregnancy failures with the same partner before 20 weeks of gestation, affecting 2%–5% of pregnant women and with an increasing trend (Koert et al., 2019 ).
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Alpha-enolase 1 knockdown facilitates the proliferation and invasion of villous trophoblasts by upregulating COX-2.
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