DNMT1 expression partially dictates 5-Azacytidine sensitivity and correlates with RAS/MEK/ERK activity in gastric cancer cells.

Epigenetics · 2023 · PMC10496526 · PMID 37691391

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highly significantno p-value reported

Analysis revealed that among the genes showing highly significant correlations with DNMT1 expression in TCGA GC samples, numerous MEK/ERK pathway-dependent genes were enriched, which included ETS-1, E2F1, and CCND1 ( Figure 5a ).

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