Pharmaceutical efficacy of novel human-origin <i>Faecalibacterium prausnitzii</i> strains on high-fat-diet-induced obesity and associated metabolic disorders in mice.

Front Endocrinol (Lausanne) · 2023 · PMC10497875 · PMID 37711887

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a decreasing trendno p-value reported

prausnitzii strains appeared to show a decreasing trend in its relative abundance.

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an increasing trendno p-value reported

The expression levels of CD36 (p < 0.01), FAS (p < 0.05), and LDL (p < 0.01) mRNAs increased significantly after HFD feeding compared to the low-fat feeding group (normal group), but ACC1 showed an increasing trend in the HFD group.

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