Inflammation and the pathological progression of Alzheimer's disease are associated with low circulating choline levels.

Acta Neuropathol · 2023 · PMC10499952 · PMID 37548694

Europe PMC DOI

hedged sentences

0.0226

closest p · 0.5× alpha

0.0556

boldest claim

The sentences

highly significantP = 0.0226actually significant

As with plaque density, we found highly significant negative correlations between choline (Fig. 1 n; r 30 = − 0.4020, P = 0.0226) and Braak stage, but not between ACh and Braak stage (Fig. 1 o).

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a trend toward significanceP = 0.0556so close (0.05 < p ≤ 0.1)

5 j), but a trend toward significance between soluble Aβ 42 and ACh (Fig. 5 k; r 11 = − 0.5421, P = 0.0556).

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