Influenza virus decreases albumin uptake and megalin expression in alveolar epithelial cells.

The results revealed a decreasing trend in LRP2 transcription levels at the 6 h time point and a significant downregulation at 24 h post-inoculation.

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When we analyzed the phosphorylation levels of GSK3β, we found an increasing trend during the experimental time frame (as opposed to de-phosphorylation, which is associated with activation of the kinase), indicating that there was no activation of GSK3β in our setting ( Supplementary Figure 2D ).

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