Identification of novel genetic risk factors of dilated cardiomyopathy: from canine to human.

Consequently, the association of this variant with echocardiographic changes in the entire echocardiographic Dobermann cohort (“echo only,” “echo + arrhythmia,” “CHF,” and “healthy” subcohorts; Utrecht cases; and the Uppsala cohort) was highly significant ( P = 1.72 × 10 −11 , χ 2 = 45.26, df = 1).

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