Barely Significant
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Peri-operative pharmacokinetics of cefazolin prophylaxis during valve replacement surgery.

PLoS One · 2023 · PMC10511078 · PMID 37729151

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may be significantno p-value reported
Given that cefazolin is a hydrophilic drug, the magnitude of the effect of CPB on cefazolin PK may be significant.

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