An intracellular isotropic diffusion signal is positively associated with pubertal development in white matter.

Dev Cogn Neurosci · 2023 · PMC10511341 · PMID 37717292

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There was a highly significant relationship between average PDSS and age (slope = 0.118 PDSS/month; 95 % CI: [0.096, 0.141], p < 0001); which remained true for both females (slope = 0.212 PDSS/year; 95 % CI: [0.181, 0.244], p < 0.001) and males (slope = 0.049; 95 % CI: [0.02, 0.078], p = 0.001), but the slope for rate in change in average PDSS/month was greater for females than for males (p < 0.001).

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