UV-radiation and MC1R germline mutations are risk factors for the development of conventional and spitzoid melanomas in children and adolescents.

EBioMedicine · 2023 · PMC10511785 · PMID 37716236

Europe PMC DOI

hedged sentence

0.0020

closest p · 0.0× alpha

0.0020

boldest claim

The sentences

highly significantp = 0.002actually significant

borderline significantp = 0.055so close (0.05 < p ≤ 0.1)

We indeed found a highly significant enrichment of R151C in melanoma cases compared to non-cancer controls (p = 0.002, Fisher’s exact test, Supplementary Table S3 ) and borderline significant enrichment of V92M (p = 0.055, Fisher’s exact test) and R160W (p = 0.053, Fisher’s exact test).

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