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Mesenchymal Stem Cell Extracellular Vesicles from Tissue-Mimetic System Enhance Epidermal Regeneration via Formation of Migratory Cell Sheets.

Tissue Eng Regen Med · 2023 · PMC10519905 · PMID 37515738

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an increasing trendno p-value reported
EMT-like and epidermal regeneration of KCs exhibit dose-dependent response to ASC-EVs KC metabolic and migratory activity exhibited a decreasing trend when treated with 2D-EVs (R 2 = 0.42 and 0.98, respectively) but an increasing trend when treated with 3D-EVs (R 2 = 0.76 and 0.96, respectively); whereas KC proliferative activity exhibited a positive dose response for both 2D-EVs (R 2 = 0.97) and 3D-EVs (R 2 = 0.96) (Fig. 6 A).

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