We then quantified the stimulus-locked responses at the six normalized angles and found that the Aux-KO mice showed smaller response to the preferred orientation that was marginally significant compared to WT mice ( Figure 4 D, Normalized angle −2: U = 67097, p = 1, Orientation −1: U = 66186, p = 1, Orientation 0: U = 74750, p = 0.07, Orientation 1: U = 65266, p = 1, Orientation 2: U = 62105, p = 0.94, Orientation 3: U = 68395, p = 0.94, Mann-Whitney U test with FDR-BH correction).
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Impaired pre-synaptic plasticity and visual responses in auxilin-knockout mice.
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