3 , 34 Across various CCA studies, the presence of cirrhosis, as well as hepatitis B and C, was not associated with shorter disease‐free survival, 34 and the results on OS in patients with cirrhosis or chronical hepatitis B infection are disparate, with an apparent trend towards shorter OS in these patients. 35 , 36 To date, the vast majority of iCCA studies investigating clinical prognostic factors do not report on either body composition, steatosis, or MAFLD as an iCCA aetiology or as a prognostic factor. 34 , 37 Recently, an Italian study reported that patients fulfilling NASH criteria had an inferior OS after iCCA surgery but did not observe a difference in TTR between aetiologies.
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Body composition is associated with disease aetiology and prognosis in patients undergoing resection of intrahepatic cholangiocarcinoma.
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