Genetic Variants in the Mitochondrial Thymidylate Biosynthesis Pathway Increase Colorectal Cancer Risk.

Curr Oncol · 2023 · PMC10529222 · PMID 37754498

Europe PMC DOI

hedged sentence

0.0010

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp = 0.001actually significant

Heterozygous (AC) carriers of the A1298C variant demonstrated highly significant protection against CRC development (RR = 0.2, p = 0.001), while a two-fold higher risk for CRC was estimated for homozygous genotype (CC) carriers.

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