Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar Disorder.

J Pers Med · 2023 · PMC10533016 · PMID 37763162

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borderline significanceno p-value reported

(2013) found a tendency towards a higher occurrence of the C (Val) allele of rs6265 and borderline significance for the Met/Met genotype in patients with bipolar disorder, type I (BD-I), bipolar disorder type II (BD-II), and schizoaffective disorder, bipolar type.

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an increasing trendno p-value reported

T-carriers of rs61888800 demonstrated lower expression of BDNF in the frontal cortex and higher expression in the cerebellum, with an increasing trend for the T-allele expression in the putamen [ 150 ].

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