Castration promotes the browning of the prostate tumor microenvironment.

Cell Commun Signal · 2023 · PMC10536697 · PMID 37770940

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almost significantno p-value reported

Three weeks after the implantation, tumor volumes of TRAMP-C1 cells injected in WAT fragments (TRAMP-C1 WAT ) were significantly higher than tumors derived from TRAMP-C1 cells injected in Matrigel (TRAMP-C1 naïve ) while the growth of TRAMP-C1 cells injected in brown/beige fragments (TRAMP-C1 BAT ) was equal to controls and showed an almost significant reduction compared to that of cells injected in WAT fragments.

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