Construction of a plasmid-free L-leucine overproducing Escherichia coli strain through reprogramming of the metabolic flux.

Biotechnol Biofuels Bioprod · 2023 · PMC10541719 · PMID 37775757

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an increasing trendno p-value reported

The accumulation of l -leucine showed an increasing trend with increasing number of gene copies, with strain LEU05 carrying three copies of leuA , producing slightly more of the amino acid (up to 2.1 g/L) than strain LEU04.

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