"Redirecting an anti-IL-1β antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A".

Commun Biol · 2023 · PMC10542344 · PMID 37773269

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highly significantno p-value reported

The docked pose of the AAL160 antibody (Fv structure) with a highly significant HexRF score (ranked 4th in the database screening) suggested a target epitope that was further supported by the PpRF predicted interaction between GLN27 of CDR L1 and LEU74 in IL-17A described above.

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