Glomerular volume correlated positively with tubular area ( R = 0.26, p = 0.03) and with PTC/tub ( R = 0.24, p = 0.047), and negatively with a trend towards significance with PTC/50,000 μm 2 ( R = − 0.21, p = 0.08).
Consistent with this theory and in line with previous literature, the current study shows a positive and significant association of glomerular volume with blood pressure, waist/hip-ratio and BSA and borderline significant with BMI, all established risk factors of CKD (i.e., nephron loss) [ 38 – 40 ].