7 In snails, Cd/CuMT transcription occurs constitutively at very low levels and is unresponsive to metal exposure, suggesting that Cd/CuMT is of only marginal significance for the overall metal balance. 7 , 8 Even though unselective, the behavior of Cd/CuMT in C. aspersum resembles more the one of CuMT than CdMT and was thus also described as a non-optimized CuMT. 16 Since the metal-ion binding properties of the Cd/CuMT isoform are unspecific and unselective (for Cd 2+ and Cu + ), we prefer to call this isoform UnMT to more clearly distinguish it from the CdMT and the CuMT isoforms.
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